H‑Med header manifold specification#
Role: Medical output header for IPD‑12
Intake rails: molecular, physiological, anatomical, healthcare
Outputs: risk, progression, intervention, target discovery
1. Intake rails (conceptual)#
- Molecular rail:
Role: encodes molecular/omics state (genes, proteins, pathways). - Physiological rail:
Role: encodes organ/system dynamics (hemodynamics, electrophysiology, metabolism). - Anatomical rail:
Role: encodes structural context (tissue, organ geometry, lesion location). - Healthcare rail:
Role: encodes clinical/EHR context (diagnoses, labs, therapies, outcomes).
These four rails are fed by IPD‑12 substrate feeds and dimensional rails, but are named in medical terms for clarity.
2. H‑Med header outputs#
- Risk:
Meaning: probability and severity of adverse events (disease onset, progression, complications). - Progression:
Meaning: trajectory of disease or recovery over time and across scales. - Intervention:
Meaning: candidate therapies, dosing strategies, timing, and regimen selection. - Target discovery:
Meaning: candidate molecular/physiological/anatomical targets for new interventions.
H‑Med is thus the medical exhaust manifold: it turns multi‑scale intake rails into clinically meaningful outputs.
H‑Med header manifold SVG (h_med_header.svg)#
<svg xmlns="http://www.w3.org/2000/svg" width="480" height="240" viewBox="0 0 480 240">
<!-- Title -->
<text x="240" y="25" font-size="16" text-anchor="middle">H‑Med Header</text>
<!-- Intake rails (left) -->
<line x1="40" y1="70" x2="150" y2="70" stroke="black" stroke-width="3"/>
<text x="45" y="65" font-size="11">Molecular</text>
<line x1="40" y1="100" x2="150" y2="100" stroke="black" stroke-width="3"/>
<text x="45" y="95" font-size="11">Physiological</text>
<line x1="40" y1="130" x2="150" y2="130" stroke="black" stroke-width="3"/>
<text x="45" y="125" font-size="11">Anatomical</text>
<line x1="40" y1="160" x2="150" y2="160" stroke="black" stroke-width="3"/>
<text x="45" y="155" font-size="11">Healthcare</text>
<text x="95" y="190" font-size="10" text-anchor="middle">Multi‑scale medical intake rails</text>
<!-- Header block -->
<rect x="150" y="60" width="180" height="120" fill="none" stroke="black" stroke-width="3"/>
<text x="240" y="120" font-size="14" text-anchor="middle">H‑Med</text>
<!-- Output channels (right) -->
<line x1="330" y1="70" x2="440" y2="70" stroke="black" stroke-width="3"/>
<text x="435" y="65" font-size="11" text-anchor="end">Risk</text>
<line x1="330" y1="100" x2="440" y2="100" stroke="black" stroke-width="3"/>
<text x="435" y="95" font-size="11" text-anchor="end">Progression</text>
<line x1="330" y1="130" x2="440" y2="130" stroke="black" stroke-width="3"/>
<text x="435" y="125" font-size="11" text-anchor="end">Intervention</text>
<line x1="330" y1="160" x2="440" y2="160" stroke="black" stroke-width="3"/>
<text x="435" y="155" font-size="11" text-anchor="end">Target Discovery</text>
<text x="240" y="215" font-size="10" text-anchor="middle">
Intake (molecular/physiological/anatomical/healthcare) → H‑Med → risk/progression/intervention/targets
</text>
</svg>